Welcome to Physical Biology of the Cell 2013 at the National Centre for Biological Sciences.

The course takes places on 9/2 - 9/6.



This intensive week-long mini-course explores the way that physical and mathematical models can be used to understand biological systems.  The course begins by examining the way in which simple order of magnitude estimates can be used to provide insights into problems ranging from the fidelity of protein translation to how far a bird can fly without stopping.  This is followed by the use of statistical mechanics to explore problems in regulatory biology.   Some examples include the physics of post-translational modifications, how cells make transcriptional decisions and the precision with which embryonic development takes place.  The next part of the course focuses on how organisms pack and access their genomes.  We start with a description of the problem of viral DNA packing and then turn to the study of the eukaryotic nucleosome. From there, we turn to the study of the cytoskeleton and its impact on cell shape and motility.