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Textbooks
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Physical Biology of
the Cell ISBN: 0815344503 |
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Street Fighting Mathematics ISBN: 9780262514293 |
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The Art of Insight in Science and Engineering: Mastering Complexity ISBN: 97802622526548 |
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Guesstimation: Solving the World's Problems on the Back of a Cocktail Napkin by Weinstein and Adam ISBN: 0691129495 |
Daily Schedule:
8:30am: Breakfast served in the Banbury Conference Center
9:00am -12noon – lectures Banbury Conference Center
12noon -1:00pm – lunch Banbury Conference Center
1:00pm - 5:30pm – lectures Banbury Conference Center
2:30pm – coffee break Banbury Conference Center
6:15pm -7:30pm – cocktails and dinner at the Robertson House
8:00pm – 10:00pm– lectures Banbury Conference Center
| DATE | TOPIC | RELEVANT READINGS (papers are linked below and can also be found on the Files page) |
INSTRUCTORS |
| Sunday, 3/1 | A feeling for the numbers in biology. Sizes, rates, concentrations, energies and information. Key probability distributions for biology. An introduction to Matlab and the image analysis/gene regulation project for the week. | Joe Blitzstein, Sanjoy Mahajan, Rob Phillips, Hernan Garcia, Griffin Chure | |
| Monday, 3/2 | A first exposure to statistical mechanics. Statistical mechanics and binding problems. Using statistical mechanics to explore regulatory biology. Analyzing gene expression data with Matlab. Biological fidelity. | Joe Blitzstein, Sanjoy Mahajan, Jané Kondev, Rob Phillips, Hernan Garcia, Griffin Chure | |
| Tuesday, 3/3 | Physics of chromosome packing. Sequencing as a biophysical tool and examples such as nucleosome positioning. Statistical mechanics of chemotaxis. Matlab project continued. |
Jané Kondev, Rob Phillips, Hernan Garcia, Griffin Chure | |
| Wednesday, 3/4 | Flies by the numbers. Reaction-diffusion equations and the developing fly embryo. Gene dosage effects and the statistical mechanics of gene expression. Image segmentation using Matlab continued. |
DNA-encoded nucleosome organization Mechanism of Protein Access to Specific DNA Sequences in Chromatin |
Hernan Garcia, Rob Phillips, Griffin Chure |
| Thursday, 3/5 | Cell biology at membranes. The costs of traffic – curvature elasticity and all that. Membranes and matlab continued. Dynamin and membrane tubules. Membrane permeability and membrane proteins. Vision estimates and MWC model. Final perspective on physical biology. | Patricia Basserau, Rob Phillips, Hernan Garcia, Griffin Chure | |
| Friday, 3/6 | Population genetics and evolution. Information theory and entropy. |
Aleksandra Walczak, Rob Phillips, Hernan Garcia, Griffin Chure | |
| Saturday, 3/7 (8:30 - 11:30 am) | Final perspective on physical biology. | Rob Phillips, Hernan Garcia, Griffin Chure |