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Course Instructor: Rob Phillips

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Mechanisms of membrane deformation. Curvature in a lipid bilayer membrane is created in five important ways: (a) lipid composition; (b) protein inclusions; (c) cytoskeleton and motor proteins; (d) scaffolding; (e) helix insertion into one leaflet.

Source: McMahon and Gallop; Membrane curvature and mechanisms of dynamic cell membrane remodelling, Nature, Dec 2005; 438(7068):590.


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